Developing Viability Index for Machine Perfused Livers
Recruiting
N/A
Interventional Study
Liver Cirrhoses
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 75
- Sex
- Any
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 60 (estimated)
- Sponsor
- Massachusetts General Hospital · Other
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About This Trial
Machine perfusion technology is nearing the point of rescuing discarded liver grafts in the hope of proving them to be or improving them to the point of being transplantable. However, there are no validated metrics to determine transplantability after machine perfusion. This study involves collecting biopsies from transplanted livers before and after implantation to correlate metabolite and gene e…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Male or female 18-75 years of age.
* Candidate for a deceased-donor liver allograft.
Exclusion Criteria:
* Seropositivity for HIV-1.
Contacts