Inflammatory Mediators of Acute Kidney Injury in Intensive Care
Recruiting
Observational Study
Sepsis
Surgery
Acute Kidney Injury
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 100 (estimated)
- Sponsor
- Uppsala University · Other
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About This Trial
Acute kidney injury (AKI) affects more than 50% of patients admitted to the intensive care unit. The most common underlying cause is sepsis. Severe AKI in combination with sepsis is associated with high mortality. The mechanisms for sepsis-induced AKI are largely unknown. Our hypothesis is that the inflammatory response to an infection cause collateral damage to host tissue and contributes to the …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Patients admitted to the intensive/post operative care unit
* with septic shock or
* post major surgery or
* after intoxication with a chemical compund
Exclusion Criteria:
* Pregnancy or
* Breast feeding or
* Chronic kidney disease or
* intoxication with nephrotoxic compund o…
Contacts