Genetic Study of Unusual Responses in Cancer Treatment

Genomic Investigation of Unusual Responders

Recruiting Observational Study
Cancer Breast Cancer Non-small Cell Lung Cancer Colorectal Cancer Genitourinary Cancer Gynecological Cancer Upper Aerodigestive Tract Cancer Pancreatobiliary Gastrointestinal Cancer Melanoma (Skin) Rare Cancer Carcinoma of Unknown Primary
No Study Drug Researchers observe your health over time — no experimental treatment is given.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
100 (estimated)
Sponsor
University Health Network, Toronto · Other
Who this trial is looking for

This trial is looking for patients who have had an unusual reaction to cancer treatment, either very good or very poor. Participants will have their tumor samples tested to understand why they responded differently to the treatment.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have had an exceptionally good or poor response to cancer treatment.
  • I have enough archived tumor tissue available for testing.
  • I am deceased but have tissue stored for research access.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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Answer a few quick questions to see if you may meet the eligibility requirements.

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About This Trial
Studies have shown that tumors from the same patient may respond very differently to the same therapeutic agents. This study aims to investigate the genetic basis of tumors that respond abnormally well or poorly to therapeutic agents in an effort to understand the fundamental genetic basis of this response. The present protocol seeks to retrospectively perform Exome, next-generation (DNA) sequenci…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. The patient must have either an exceptionally good or poor response to treatment, as indicated by their treating physician. 1. The exact definition of this is adaptable to the disease but a suggested guideline is a Complete Response, Partial Response or progression free i…
Contacts

Celeste Yu

416-946-4501

celeste.yu@uhn.ca

CONTACT

Elizabeth Shah

416-946-4501

elizabeth.shah@uhn.ca

CONTACT