Heterogeneously Hypofractionated Radiotherapy for Locally Advanced NSCLC

Recruiting N/A Interventional Study
Stage III Non-small-cell Lung Cancer Stage IV Non-small Cell Lung Cancer Radiotherapy Side Effect
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
151 (estimated)
Sponsor
Danish Lung Cancer Group · Other
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About This Trial
The options for patients with locally advanced non-small cell lung cancer (NSCLC) who are not candidates for a standard definitive chemoradiotherapy regime are meagre. These are patients who are not fit for a chemoradiotherapy schedule of 66 Gy in 2 Gy fractions due to either tumour extent, resulting in excessive dose to the healthy tissue in the thorax, or with performance status not supporting s…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Histologically or cytological confirmed locally advanced, inoperable NSCLC. * Age ≥18 years. * Signed informed consent. * Performance status 0-2. * Able to comply with study and follow-up procedures. * Fertile women must have a negative pregnancy test. Fertile men and women mu…
Contacts

Azza A Khalil, MD, PhD

+4578462556

azzakhal@rm.dk

CONTACT

Marianne M Knap, MD, PhD

+4578462556

mariknap@rm.dk

CONTACT