Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service
Recruiting
N/AInterventional Study
Anesthesia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 65
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
94 (estimated)
Sponsor
Hospital for Special Surgery, New York · Other
Who this trial is looking for
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A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block (ACB) vs. (2) PAI, IPACK and continuous adductor canal block catheter (ACC).
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* Patients with osteoarthritis scheduled for a primary total knee arthroplasty with a participating surgeon
* Planned use of regional anesthesia
* Ability to follow study protocol
* English speaking (secondary outcomes include questionnaires validated in English only)
* Lives wi…
Inclusion Criteria:
* Patients with osteoarthritis scheduled for a primary total knee arthroplasty with a participating surgeon
* Planned use of regional anesthesia
* Ability to follow study protocol
* English speaking (secondary outcomes include questionnaires validated in English only)
* Lives within one hour of the hospital
* Has a smart phone
Exclusion Criteria:
* Hepatic or renal insufficiency
* Younger than 18 years old or older than 65 years ol
* Patients undergoing general anesthesia
* Allergy or intolerance to one of the study medications
* BMI \>40
* Diabetes
* American Society of Anesthesiologists (ASA) status III or IV
* Chronic gabapentin/pregabalin use (regular use for longer than 3 months)
* Patients with chronic pain (from a referral to chronic pain service) or a pain catastrophizing scale (PCS \>30)
* Patients with severe valgus deformity or flexion contracture
* Patients unable to follow home catheter instructions and unwilling to go home with an infusing catheter
* Patients who have no home caregivers in the event that a catheter is to be sent home with the patient
* Patients with planned stay at rehab facility (to avoid medical device being tampered with at the rehab facility)
* Non-English speakers (secondary outcomes include questionnaires validated in English only)
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