No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Health Services Research
Participants needed
726 (estimated)
Sponsor
University Hospital, Strasbourg, France · Other
Who this trial is looking for
This trial is looking for adults who want to learn more about how light affects sleep and mental health. Participants may have certain health conditions or be healthy themselves.
Are You a Good Fit for This Trial?
You may be able to join if
I am 18 years or older
I consent to participate in the study
I am linked to a social protection scheme
I have a primary sleep-wake disorder
I have a neurological disorder affecting sleep
I have a psychiatric disorder affecting sleep
I have an ophthalmological condition affecting how I see light
I have photosensitivity affecting sleep
You may not be able to join if
I have age-related macular degeneration or maculopathies
I have a cataract that significantly affects my vision
I have chorioretinal neovascularization
I am currently involved in another study that disqualifies me
I cannot understand the information given to me
I am under legal protection
I am under guardianship or curatorship
I am pregnant or breastfeeding
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The light has visual and non-visual effects on organism and can act on the behavior, the mood, the cognition and the sleep. These effects are mediated by "classical" retina photoreceptors which allow vision (rods, cones) but also melanopsin cells. The non-visual effects of light seems to be altered in many neurological, psychiatric or ophtalmological conditions but their exact role in the pathogen…
The light has visual and non-visual effects on organism and can act on the behavior, the mood, the cognition and the sleep. These effects are mediated by "classical" retina photoreceptors which allow vision (rods, cones) but also melanopsin cells. The non-visual effects of light seems to be altered in many neurological, psychiatric or ophtalmological conditions but their exact role in the pathogenesis remains poorly understand. The purpose of the study is to increase our knowledge of the non-visual effects of light and establish new therapeutic applications
Trial Locations
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Facility
City
State
Country
Status
Eligibility Criteria
Inclusion Criteria:
* Man or woman
* Aged 18 years or older
* Subject having signed a free and informed consent
* Subject affiliated to a social protection scheme Arm 1 :Subjects with primary sleep-wake disorder Arm 2 : subjects presenting a neurological pathology with disorder of the controls of t…
Inclusion Criteria:
* Man or woman
* Aged 18 years or older
* Subject having signed a free and informed consent
* Subject affiliated to a social protection scheme Arm 1 :Subjects with primary sleep-wake disorder Arm 2 : subjects presenting a neurological pathology with disorder of the controls of the wake and the sleep Arm 3 : subject presenting a psychiatric pathology pathology with disorder of the controls of the wake and the sleep Arm 4 : subject presenting an ophthalmological pathology with possible alteration of the photoreception and / or phototransduction Arm 5 : subjects with photosensitivity with regulation disorder of sleep and wake Arm 6 : healthy subject
Exclusion Criteria:
Age-Related Macular Degeneration (AMD) and all maculopathies (retinopathies pigmentosa, macular involvement of diabetes)
* Cataract with significant vision loss \<5/10
* Chorioretinal neovascularization
* Subject in exclusion period determined by previous or current study
* Impossibility to give the subject information enlightened (subject in emergency situation, difficulties of understanding the subject, ...)
* Subject under the protection of justice
* Subject under guardianship or curatorship
* Pregnancy / Breastfeeding
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