Post-Op Pain Control for Prophylactic Intramedullary Nailing.

Recruiting Phase 3 Interventional Study
Bone Metastases Lymphoma Multiple Myeloma Opioid Use Pain
Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Treatment
Participants needed
60 (estimated)
Sponsor
St. Louis University · Other
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About This Trial
Nationally, the opioid crisis has become a major epidemic with increasing mortality rates each year. Orthopedic surgeons routinely prescribe narcotics instead of NSAIDs for post-op pain control because of risk of delayed healing and nonunion due to NSAID use. Orthopedic oncology, however, has a unique subset of patients that undergo prophylactic placement of intramedullary femoral nails. Because n…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Femoral Shaft or Neck bone lesion 2. 18 years old or greater 3. Plan to undergo prophylactic intramedullary nailing of one femur Exclusion Criteria: 1. Concurrent pathologic fracture 2. History of advanced renal impairment (eGFR\<30mL/min) 3. History of Peptic Ulcer Disease…
Contacts

David Greenberg, MD

314-617-3410

david.greenberg@health.slu.edu

CONTACT

Allison Gruender, MSN

314-617-3406

allison.gruender@health.slu.edu

CONTACT