Remote Ischaemic Preconditioning in Transplantation (RIPTRANS)

Recruiting N/A Interventional Study
Transplant Dysfunction
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
496 (estimated)
Sponsor
Helsinki University Central Hospital · Other
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About This Trial
Remote ischemic preconditioning (RIPC) is a concept where remotely induced ischemia produces protection against ischemia-reperfusion injury in a remote organ. RIPC has been studied extensively in animal models and heart surgery, but it's benefit in transplantation has been studied less. The primary aim of this study is to find out whether RIPC performed in a donor in donation after brain-death (DB…
Trial Locations
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Eligibility Criteria
Donor Inclusion Criteria: * Brain-dead organ donor with a plan of harvesting at least one kidney Donor Exclusion Criteria: * Haemodynamically unstable donor * Age below 18 years * Planned organ recipients are recruited to another prospective trial, which prevents participation in this trial. All…
Contacts

Ville Sallinen, MD, PhD

+358-9-4711

ville.sallinen@helsinki.fi

CONTACT

Aki Uutela, MD

+358-9-4711

aki.uutela@hus.fi

CONTACT