Mechanisms of Rumination Change in Adolescent Depression

Recruiting N/A Interventional Study
Major Depressive Disorder Mood Disorders
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
14 – 17
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
183 (estimated)
Sponsor
Ohio State University · Other
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About This Trial
This study will evaluate whether a newer treatment, rumination-focused cognitive behavioral treatment, which includes mindfulness and can be used to reduce ruminative habits, change ways in which key brain regions interact with each other (e.g.., often called connectivity), and whether these changes in habits and brain connectivity can reduce the risk for recurrence of depression in the next two y…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Previous diagnosis of Major Depressive Disorder (full or partial remission for at least two weeks) according to Diagnostic and Statistical Manual (DSM-V) criteria confirmed by the Kiddie Schedule for affective disorders (KSADSPL). Partial remission is defined as not meeting fu…
Contacts

Scott A Langenecker, Ph.D.

734-276-3889

scott.langenecker@osumc.edu

CONTACT

Caty Escobar, M.S.

301-648-3426

caty.escobar@osumc.edu

CONTACT