Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style Intervention
Recruiting
N/A
Interventional Study
Non-Alcoholic Fatty Liver Disease
Obesity, Morbid
Brown Fat
Metabolic Disease
Diabetes Mellitus
Insulin Resistance
Abdominal Subcutaneous Fat
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 80 (estimated)
- Sponsor
- Chinese University of Hong Kong · Other
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About This Trial
The study is aimed * To quantify the change of adipose tissues, triglyceride in liver and pancreas and cholesterol after lifestyle intervention or bariatric surgery. * To test the hypothesis that Brown fat is an independent biomarker for the development of Non Alcoholic Fat Liver Disease (NAFLD) * To study the association among Brown fat, NAFLD and obesity.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* BMI ≥ 25-30 kg/m2
* BMI ≥ 30 kg/m2 with Metabolic syndrome
* BMI ≥ 35 kg/m2 for morbid obesity
Exclusion Criteria:
* Other kind of hepatic diseases
* Under medications known to affect liver fat
* Waist circumference ≥ 150 cm
* Weight ≥ 250 kg
* MRI contraindications
Contacts