No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
60 and older
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
125 (estimated)
Sponsor
Pennington Biomedical Research Center · Other
Who this trial is looking for
This trial is looking for older African American adults who want to see if an exercise program can help reduce the risk of Alzheimer's disease. Participants will join a group exercise program and attend regular sessions.
Are You a Good Fit for This Trial?
You may be able to join if
I identify as African American
I am 60 years or older
I am willing to accept randomization
I can attend group sessions
I do not have plans to move during the study
I can safely participate in regular exercise
I do not engage in regular physical activity
I can perform physical activities
You may not be able to join if
I have cognitive impairment that affects my ability to participate
I am unable to give written consent
I cannot attend group sessions
I have conditions that prevent me from exercising
My doctor has advised that I should not participate
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The RAATE proposal is designed to determine the effects of physical activity on risk factors for Alzheimer's Disease in older African American adults. The study will compare a physical activity program to an active control group. There are three main objectives of the protocol: 1) to determine if a physical activity intervention tailored to older African American adults is effective in modifying c…
The RAATE proposal is designed to determine the effects of physical activity on risk factors for Alzheimer's Disease in older African American adults. The study will compare a physical activity program to an active control group. There are three main objectives of the protocol: 1) to determine if a physical activity intervention tailored to older African American adults is effective in modifying cognitive function associated with Alzheimer's Disease, 2) to determine if a physical activity intervention tailored to older African American adults is effective in modifying brain function and structure associated with Alzheimer's Disease, and 3) to determine if a physical activity promotion intervention tailored to African American adults is effective at enhancing physiological parameters. The primary endpoints for the study are episodic memory and executive functioning. The secondary outcomes include anthropometry, blood pressure, brain activation, cerebral blood flow, volume of whole brain and white matter hyperintensities, cardiorespiratory fitness, objectively measured physical activity, circulating hormones, and telomere length.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. self- identify as African American
2. 60 years and older
3. willing to accept randomization
4. willing to attend group sessions
5. lacking plans to move during the study period
6. free of conditions that would make regular exercise unsafe (e.g. uncontrolled asthma, severe sic…
Inclusion Criteria:
1. self- identify as African American
2. 60 years and older
3. willing to accept randomization
4. willing to attend group sessions
5. lacking plans to move during the study period
6. free of conditions that would make regular exercise unsafe (e.g. uncontrolled asthma, severe sickle cell disease, etc.)
7. not engaged in regular physical activity
8. Short Physical Performance Battery score \>/= 4
9. physically capable of exercise,
Exclusion Criteria:
1. cognitive impairment that would interfere with participating in group interactions
2. unwilling to give written informed consent
3. inability to attend group sessions
4. conditions that prevent regular exercise
5. conditions that the medical or principal investigator determine to warrant exclusion
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