Quadriceps vs Hamstrings for ACL Surgery in Young Patients

Soft-tissue Quadriceps Autograft ACL-reconstruction in the Skeletally-immature vs. Hamstrings

Recruiting N/A Interventional Study
ACL - Anterior Cruciate Ligament Rupture
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
10 – 18
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
352 (estimated)
Sponsor
McMaster University · Other
Who this trial is looking for

This trial is looking for young people aged 10 to 18 who need surgery for a torn ACL. Participants will have a choice between using a tendon from their quadriceps or hamstrings for the surgery and will be followed for 24 months to see how well the surgery works.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am aged 10-18 years.
  • I have a confirmed torn ACL.
  • I am suitable for ACL reconstruction surgery.
  • I have evidence of skeletal immaturity in X-ray or MRI.
  • I was involved in sports before my injury.
  • I can understand the language of the clinical site.
  • I provide informed consent and/or assent.

You may not be able to join if

  • I have a significant cartilage injury that needs more than minor treatment.
  • I have had surgery for a fracture in my knee.
  • I have other knee problems that need surgery.
  • I have had previous ACL surgery in either knee.
  • I have had a serious injury to my knee growth plates.
  • I have had synthetic materials used in my previous knee surgery.
  • I have a condition that causes joint inflammation.
  • I have serious medical issues that need daily help.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial
To date, the use of the quadriceps tendon as an autograft option in primary paediatric Anterior Cruciate Ligament (ACL) reconstruction has not been well studied. The 2018 International Olympic Committee (IOC) Consensus Statement now outlines the quadriceps tendon as a possible autograft option. However, no Randomised Control Trial (RCT) has examined the efficacy of the quadriceps tendon autograft …
Trial Locations
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Eligibility Criteria
Inclusion Criteria 1. Patients aged 10-18 years. 2. History, physical exam, and magnetic resonance imaging (MRI) or arthroscopic image confirmation of ACL insufficiency. 3. Suitable for anatomic, single-bundle arthroscopic-assisted ACL reconstruction. 4. X-ray or MRI evidence of skeletal immaturity…
Contacts

Darren de SA, MD, FRCSC

9059232126

darren.desa@medportal.ca

CONTACT

Nicole Simunovic, MSc

(289) 237-3224

simunon@mcmaster.ca

CONTACT