No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
0 – 21
Sex
Any
Study type
Interventional
Purpose
Diagnostic
Participants needed
100 (estimated)
Sponsor
University of Wisconsin, Madison · Other
Who this trial is looking for
This trial is looking for children aged 0-21 with kidney issues like urinary tract infections. Participants will undergo a new type of MRI that doesn’t require injections, sedation, or radiation.
Are You a Good Fit for This Trial?
You may be able to join if
I am a child or young adult aged 0-21 years.
I have a febrile urinary tract infection or diagnosed pyelonephritis.
I am undergoing a DMSA scan.
I have had more than one urinary tract infection in the past year.
You may not be able to join if
I have no signs of infection in my urine analysis.
I have a negative urine culture.
I am not comfortable having a Quick MRI.
I have conditions that prevent me from getting an MRI.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The investigators propose a new imaging method for children born with congenital anomalies of the urinary tract that is a rapid, injection-, sedation-, and radiation-free alternative: the quick renal MRI. This proposal hypothesizes that the quick renal MRI has high validity compared to current radiologic standard for renal infection and scarring, the 99mTechnetium-dimercaptosuccinic acid (99mTc- D…
The investigators propose a new imaging method for children born with congenital anomalies of the urinary tract that is a rapid, injection-, sedation-, and radiation-free alternative: the quick renal MRI. This proposal hypothesizes that the quick renal MRI has high validity compared to current radiologic standard for renal infection and scarring, the 99mTechnetium-dimercaptosuccinic acid (99mTc- DMSA) renal scan in the detection of acute renal infections and scars. If the quick renal MRI is accurate, it could potentially replace the DMSA scan for those specific questions and ease the burden of testing for children with chronic renal disease. Findings from these studies will provide preliminary data and rationale for a multi-centered study to further test this new technology.
Participants will be 0-21 years of age and can expect to be on study for from 1 week (if enrolled in Aim 1) to 6 months (if enrolled in Aim 2).
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* Aim 1:
* Patient is admitted to American Family Children's Hospital for a febrile UTI, suspected pyelonephritis, or diagnosed pyelonephritis
* Undergoing clinical DMSA scan
* Aim 2:
* Undergoing DMSA scans as a part of their routine clinical care
* History of more th…
Inclusion Criteria:
* Aim 1:
* Patient is admitted to American Family Children's Hospital for a febrile UTI, suspected pyelonephritis, or diagnosed pyelonephritis
* Undergoing clinical DMSA scan
* Aim 2:
* Undergoing DMSA scans as a part of their routine clinical care
* History of more than one UTI in the past year
Exclusion Criteria:
* Aim 1:
* No evidence of pyuria on their urine analysis
* Negative urine culture
* Not comfortable with having a Quick MRI performed
* Both aims:
* Contraindications to MRI
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