Measurement Of NT-proBNP to Predict Outcomes in Surgery
Recruiting
Observational Study
Vascular Surgical Procedure
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
200 (estimated)
Sponsor
Norfolk and Norwich University Hospitals NHS Foundation Trust · Other
Who this trial is looking for
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The team is investigating whether N-terminal pro B-type natriuretic peptide (NT-proBNP) and other cardiac markers are useful for predicting outcomes for patients undergoing vascular surgery. By measuring NT-proBNP before and after surgery, the investigators may be able to determine which patients are at risk of an adverse outcome, such as a heart attack or death.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients who are equal to or over 18 years old
* Patients scheduled to undergo elective surgery for the following procedures:
* Infrainguinal arterial reconstruction
* Aortic aneurysm
* Aorto-bifemoral bypass / or aortic endarterectomy
* Femoro-popliteal bypass
* Femoro-distal…
Inclusion Criteria:
* Patients who are equal to or over 18 years old
* Patients scheduled to undergo elective surgery for the following procedures:
* Infrainguinal arterial reconstruction
* Aortic aneurysm
* Aorto-bifemoral bypass / or aortic endarterectomy
* Femoro-popliteal bypass
* Femoro-distal bypass
* Femoral endarterectomy
* Femoro-femoral crossover
* Axillo-femoral bypass
* Elective carotid surgery
* Patients having either general or regional anaesthesia for their surgery
Exclusion Criteria:-
* Patients undergoing emergency surgery
* Those who are unable or unwilling to give informed consent
* Patients with unstable coronary syndromes (acute or recent MI with evidence of important ischemic risk by clinical symptoms or stress testing or unstable or severe angina pectoris)
* Patients with decompensated heart failure (new onset shortness of breath and rales together with echocardiographic evidence of cardiac dysfunction or deterioration of chronic heart failure despite heart failure therapy)
* Patients with chronic atrial fibrillation
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