Local Treatment for Breast Cancer Liver Metastases
BreCLIM-2 - A RCT Investigating Local Treatment for Breast Cancer Liver Metastases
Recruiting
Phase 3
Interventional Study
Breast Cancer
Liver Metastases
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Pivotal Trial
This treatment is in the last trial phase before FDA approval.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 3
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 200 (estimated)
- Sponsor
- Umeå University · Other
Who this trial is looking for
This trial is looking for people with breast cancer that has spread to the liver. Participants will receive either local treatment combined with regular cancer treatment or just the regular treatment alone.
Are You a Good Fit for This Trial?
You may be able to join if
- I am at least 18 years old
- I have signed the informed consent
- I have a history of breast cancer
- I have liver metastasis confirmed by a biopsy
- I can undergo liver surgery
- I have 1-4 liver metastases that can be surgically removed
- My liver metastasis is stable or responding to treatment
You may not be able to join if
- I have cancer that has spread outside the liver
- I have not had my primary tumor removed
- I am pregnant
- My cancer has worsened during treatment
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Breast cancer is the second most common cancer in Sweden with an incidence of 8000 per year. The role of surgery for distant breast cancer metastasis beyond local lymph nodes remains controversial even though some reports suggest there might be a survival benefit from resection of oligometastases in the liver.
The purpose of this multicentre randomized clinical trial is to evaluate local treatmen…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Signed informed consent
* \>18 years old
* ECOG 0-1
* Breast cancer history
* Breast cancer liver metastasis verified by biopsy
* Patient amendable for liver surgery and pre- and postoperative oncological treatment
* 1-4 liver metastasis amendable to surgery with functional li…
Contacts