Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic Encephalopathy
Recruiting
N/A
Interventional Study
Hepatic Encephalopathy
At a Glance
- Age
- 18 – 75
- Sex
- Any
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 40 (estimated)
- Sponsor
- The Cleveland Clinic · Other
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About This Trial
Readmission rates for patients with hepatic encephalopathy due to end stage liver disease are high. Hyperammonemia contributes significantly to encephalopathy and occurs because of impaired hepatic ureagenesis and increased skeletal muscle proteolysis. We propose a randomized, 6-month nutritional intervention in cirrhotic patients who have had at least 1 admission for hepatic encephalopathy within…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* \> 18 years of age
* cirrhosis diagnosed by clinical history and liver biopsy and/or clinical, biochemical and imaging evidence of cirrhosis
* at least 1 hospitalization for documented HE within the last 12 months.
* abdominal CT scan anytime in the past
Exclusion Criteria:
…
Contacts