Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic Encephalopathy

Recruiting N/A Interventional Study
Hepatic Encephalopathy
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At a Glance
Age
18 – 75
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
40 (estimated)
Sponsor
The Cleveland Clinic · Other
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About This Trial
Readmission rates for patients with hepatic encephalopathy due to end stage liver disease are high. Hyperammonemia contributes significantly to encephalopathy and occurs because of impaired hepatic ureagenesis and increased skeletal muscle proteolysis. We propose a randomized, 6-month nutritional intervention in cirrhotic patients who have had at least 1 admission for hepatic encephalopathy within…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * \> 18 years of age * cirrhosis diagnosed by clinical history and liver biopsy and/or clinical, biochemical and imaging evidence of cirrhosis * at least 1 hospitalization for documented HE within the last 12 months. * abdominal CT scan anytime in the past Exclusion Criteria: …
Contacts

Annette C Bellar

2166365247

bellara@ccf.org

CONTACT