Effect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell Anemia

Recruiting N/A Interventional Study
Sickle Cell Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Other
Participants needed
15 (estimated)
Sponsor
University of Pittsburgh · Other
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About This Trial
MitoQ is commercially available as a dietary supplement and it has been tested as a potential drug in other diseases, but it has never been tested in patients with sickle cell disease. The goal of this research is to study if MitoQ, a molecule that works as an antioxidant by removing potentially damaging agents in a living organism, improves platelet function in patients with sickle cell disease …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: Subjects * African American * Patients with sickle cell anemia * 18 years old or older Control * African American healthy controls * 18 years of age or older Exclusion Criteria: 1. Pregnancy, 2. Known hypertension, 3. Hemodialysis and active obstructive sleep apnea requirin…
Contacts

Mikhil N Bamne, PhD

(412) 648-6920

bamnemn2@upmc.edu

CONTACT

Jude Jonassaint, RN

412-692-2086

jonassaintjc@upmc.edu

CONTACT