No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
90 (estimated)
Sponsor
Danish Research Centre for Magnetic Resonance · Other
Who this trial is looking for
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The purpose of this study is to establish a methodological framework based on existing advanced neuroimaging technologies as a new clinical neuroimaging tool for assessment of possible affected brain connections in stroke and TIA patients. Thus, providing new insights into microstructural changes that may underline why those patients experience deficits like fatigue.
Trial Locations
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Status
Eligibility Criteria
Patient Inclusion Criteria:
* Stroke or TIA (ABCD2\>4 and/or acute Diffusion-Weighted Image (DWI) lesion).
* Modified Rankin Scale \<=2.
* As perceived by the investigator, have the ability to comply with all requirements of the study protocol.
* Have the ability to understand and sign the Informed…
Patient Inclusion Criteria:
* Stroke or TIA (ABCD2\>4 and/or acute Diffusion-Weighted Image (DWI) lesion).
* Modified Rankin Scale \<=2.
* As perceived by the investigator, have the ability to comply with all requirements of the study protocol.
* Have the ability to understand and sign the Informed Consents Form.
* Multidimensional Fatigue Inventory score \>= 12 on general fatigue.
Patient Exclusion Criteria:
* The DRCMR´s general exclusion criteria for MRI research.
* Pregnancy or lactation; human chorionic gonadotropin (hCG) urine test is offered for women \< 55 years.
* Major medical illness (for instance: anemia, diabetes mellitus, thyroid disorders, cardiovascular disease, electrolyte imbalance, etc.)
* Treated with ritalin or modafinil.
* Known uncontrolled severe malignancy.
* Known drug or alcohol addiction.
* Tiredness due to pharmaceutical side effects, as identified by the Investigator.
* Max body weight of 130 kg.
* Persons who do not wish to be informed about abnormal findings as part of the investigations.
Healthy Controls Exclusion Criteria:
* The DRCMR´s general exclusion criteria for MRI research.
* Pregnancy or lactation; urin hCG test is offered for women \< 55 years.
* Major medical illness (for instance: anemia, diabetes mellitus, thyroid disorders, cardiovascular disease, electrolyte imbalance, etc.)
* Anamnestic infection (cystitis, influenza, pneumonia, etc) the last 3 weeks.
* Known malignancy.
* Known drug or alcohol addiction.
* Tiredness due to pharmaceutical side effects.
* Max body weight of 130 kg.
* Persons who do not wish to be informed about abnormal findings as part of the investigations.
Healthy Controls Inclusion Criteria:
* Healthy
* Age- and sex-matched to patient groups.
* As perceived by the investigator, have the ability to comply with all requirements of the study protocol.
* Have the ability to understand and sign the Informed Consents Form.
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