Alpha-1 Blockade for Alcohol Use Disorder (AUD)
Recruiting
Phase 2
Interventional Study
Alcohol Use Disorder (AUD)
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 184 (estimated)
- Sponsor
- Brown University · Other
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About This Trial
The goal of this research is to replicate findings previously conducted in a pilot trial and to understand, mechanistically, the role of stress in the development of AUD pharmacotherapies that target noradrenergic blockade.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Male or female, 18 years of age
* Meet the DSM-5 criteria for AUD
* Desire to reduce or quit alcohol drinking
* Breath alcohol (BrAC) = 0.00 at each visit
* In good health as confirmed by medical history, physical examination and lab tests
* Willing to adhere to the study proc…
Contacts