EXOME Analysis Position in the Strategy of Genetic Predisposition Factors Identification in Early-onset Cancer
Recruiting
N/A
Interventional Study
Cancer
Genetic Predisposition
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 613 (estimated)
- Sponsor
- Centre Georges Francois Leclerc · Other
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About This Trial
5 to 10% of cancers are due to the presence of a constitutional genetic alteration. It can be inherited from parents (family form) or by accident, in the first moments of life after fertilization (sporadic form). In both cases, this genetic alteration is constitutional and transmissible to descendants. It is hereditary. When an hereditary early form is suspected, several well-known genes generally…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Index case:
1. Major or minor patient
2. Histological or cytological evidence of malignant tumor diagnosis
3. Patient with cancer before age 40 (or before age 30 for breast cancer).
4. Absence of anomaly found on the oncogenetic panel tested in the predisposition concerned
5. P…
Contacts