No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
21 – 80
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
30 (estimated)
Sponsor
City University of New York · Other
Who this trial is looking for
This trial is looking for people with chronic aphasia after a stroke and healthy volunteers to join a therapy program with brain stimulation. Participants will receive sessions twice a week for 8 weeks to help improve their language abilities.
Are You a Good Fit for This Trial?
You may be able to join if
I am right-handed.
I have completed high school or an equivalent level of education.
I speak English fluently without learning a second language early.
I can perform the required therapy tasks.
I had a stroke in the left side of my brain more than 6 months ago.
I have been diagnosed with aphasia.
I am not receiving any other speech therapy during the study period.
You may not be able to join if
I have failed vision or hearing tests.
I have a pacemaker or other MRI contraindications.
I am pregnant.
I have had a seizure or changed seizure medication in the past year.
I have a history of serious speech, language, psychiatric, or neurological disorders.
My hairstyle prevents electrode contact with my scalp.
I have a sensitive scalp.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The purpose of this study is to assess changes in language abilities of participants with chronic, post-stroke aphasia following an 8-week therapy period combined with brain stimulation. The investigators use a stimulation method called transcranial direct current stimulation (tDCS). The investigators cover two electrodes in damp sponges, place them on the scalp, and pass a weak electrical current…
The purpose of this study is to assess changes in language abilities of participants with chronic, post-stroke aphasia following an 8-week therapy period combined with brain stimulation. The investigators use a stimulation method called transcranial direct current stimulation (tDCS). The investigators cover two electrodes in damp sponges, place them on the scalp, and pass a weak electrical current between them. Some of this current passes through the brain and can change brain activity. One electrode is placed over language areas a bit above and in front of the left ear. The other is placed on the forehead above the right eye. Stimulation is provided twice a week for 8 weeks during aphasia therapy. The investigators believe that this stimulation may increase the effectiveness of therapy.
Trial Locations
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City
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Status
Eligibility Criteria
This study recruits individuals with post-stroke aphasia as well as a group of healthy volunteers matched for age, sex, and education.
INCLUSION Criteria:
* Right handed (pre-stroke for participants with aphasia)
* High school education or equivalent
* Native English fluency without early 2nd lang…
This study recruits individuals with post-stroke aphasia as well as a group of healthy volunteers matched for age, sex, and education.
INCLUSION Criteria:
* Right handed (pre-stroke for participants with aphasia)
* High school education or equivalent
* Native English fluency without early 2nd language exposure (before age 10)
* Ability to perform the required discourse and MRI tasks (determined via in-person screening)
Additional INCLUSION Criteria for participants with APHASIA:
* Single-event left hemisphere stroke \> 6 months prior to enrollment
* Aphasia diagnosis per Western Aphasia Battery-Revised
* Not receiving any other speech therapy for the entire study period (20 weeks)
* Ability to perform the required therapy tasks (determined via in-person screening)
EXCLUSION Criteria:
* Failed vision or hearing screening
* MRI contraindications (including pacemaker)
* Pregnancy
* History of seizure or change in seizure medication in past 12 months
* History of speech/language, psychiatric, or neurological disorder, or current serious medical condition (except chronic stroke comorbidities for participants with aphasia)
Additional EXCLUSION criteria for participants with APHASIA are:
* Unmodifiable hair style precluding scalp contact by electrodes
* Sensitive scalp by self-report
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