CAnadian CAncers With Rare Molecular Alterations (CARMA) - Basket Real-world Observational Study (BROS)
Recruiting
Observational Study
Cancer
Malignancies Multiple
Malignant Solid Tumor
Cancer, Therapy-Related
Molecular Sequence Variation
Genetic Alteration
Gene Fusion
Receptor Tyrosine Kinase Gene Mutation
RTK Family Gene Mutation
Ras (Kras or Nras) Gene Mutation
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 5,500 (estimated)
- Sponsor
- University Health Network, Toronto · Other
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About This Trial
This study will collect data on Canadian cancer patients that have uncommon/rare changes in their tumours, such as alterations/rearrangements in the genetic material inside cells - known as deoxyribonucleic acid, or DNA, which acts as a map and gives directions to the cells on how to make other substances the body needs - because some of these changes have been found to respond to different drugs …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients ≥ 18 years at cancer diagnosis
* Diagnosed with malignant tumour(s) with molecular testing completed that identified rare molecular alterations
* Accessible/available molecular testing reports/documentation to confirm type(s) of molecular alteration(s) (resulting from…
Contacts