RH Genotype Matched RBC Transfusions
Recruiting
Phase 1
Phase 2
Interventional Study
Sickle Cells Disease
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 6 Months and older
- Sex
- Any
- Trial phase
- Phase 1/2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 35 (estimated)
- Sponsor
- Children's Hospital of Philadelphia · Other
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About This Trial
To determine the feasibility and efficacy of matching donor red cells by RH genotype for a cohort of chronically transfused patients with SCD.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Subjects age \>6 months
* Diagnosis of SCD, all genotypes
* Require a period of chronic red cell transfusion therapy
* Subject/parental/guardian permission (informed consent) and if appropriate, child assent
Exclusion Criteria:
* Rare RH genotype that would preclude identifi…
Contacts