Blood Pressure Management in Hemodialysis Patients

Blood Pressure Slopes and Ultrafiltration in Hemodialysis Patients

Recruiting N/A Interventional Study
End Stage Renal Disease Hypertension Extracellular Volume Overload Intradialytic Hypotension
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
69 (estimated)
Sponsor
VA Office of Research and Development · Federal
Who this trial is looking for

This trial is looking for hemodialysis patients who have high blood pressure. Participants will have their blood pressure patterns monitored and compared to standard care to find better ways to manage blood pressure during treatment.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am a hemodialysis patient.
  • My blood pressure before dialysis is greater than 140 mmHg on average over 2 weeks.
  • My blood pressure after dialysis is greater than 130 mmHg on average over 2 weeks.

You may not be able to join if

  • I have been on hemodialysis for less than 2 months.
  • I am pregnant.
  • My average blood pressure is below 95 mmHg during the screening period.
  • My average blood pressure before or after dialysis is greater than 180 mmHg.
  • I have a drop in blood pressure greater than 60 mmHg from before to after dialysis.
  • I regularly take clonidine during dialysis.
  • I regularly take midodrine during dialysis.
  • I do not follow my blood pressure medication plan.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial
Kidney failure has been recognized as one of the most costly chronic conditions among United States Veterans. Approximately 13,000 Veterans develop kidney failure each year, and most require hemodialysis initiation. Hemodialysis patients suffer significantly increased risk of death and hospitalizations, and excessive body fluid is a major cause of this. While empiric aggressive fluid removal durin…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Hemodialysis patient * Pre-dialysis systolic blood pressure greater than 140 mmHg averaged over 2 weeks OR post-dialysis systolic blood pressure greater than 130 mmHg averaged over 2 weeks Exclusion Criteria: * HemoDialysis Vintage Less than 2 months * Pregnancy * Mean systo…
Contacts

Peter N Van Buren, MD

(214) 857-2214

peter.vanburen@va.gov

CONTACT