Carbon Ion Re-Radiotherapy in Patients With Recurrent or Progressive Locally Advanced Head-and-Neck Cancer
Recruiting
N/A
Interventional Study
Locally Advanced Head-and-Neck Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 72 (estimated)
- Sponsor
- University Hospital Heidelberg · Other
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About This Trial
After multimodal therapy of head-and-neck tumors, patients often develop local recurrence, locally progressive disease or second primary tumors. In this highly pre-treated patient cohort, therapeutic options are limited. Patients that are not candidates for salvage surgery may benefit from re-irradiation. Despite recent technical advances, re-irradiation is associated with severe side effects. Car…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Locally recurrent / progressive head-and-neck cancer after initial radiation therapy
* Microscopic or macroscopic tumor after salvage surgery
* Indication for re-irradiation
* Completed wound healing after surgical intervention
* Karnofsky-Performance-Score ≥ 60
* Age ≥ 18 yea…
Contacts