Brain Imaging Biomarkers in Patients With Brain Metastasis

Recruiting Phase 2 Interventional Study
Brain Metastases, Adult
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Diagnostic
Participants needed
90 (estimated)
Sponsor
University Health Network, Toronto · Other
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About This Trial
A biomarker is a measurable indicator of the severity or presence of some disease state. In this study, brain metastases patients who will be receiving radiation treatment, will undergo CT (Computed Tomography) and MRI (Magnetic Resonance Imaging) scans prior to and after radiation treatment to measure these biomarkers. This is a single-center phase II study to validate the predictive abilities of…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Biopsy proven primary malignancy (original biopsy is adequate as long as the brain imaging is consistent with brain metastases) * At least one index lesion with diameter \> 1cm and without imaging evidence of hemorrhage * Patients age \> 18 years of age * Patients planned for …
Contacts

David Shultz, M.D., Ph. D

416-946-6899

david.shultz@rmp.uhn.on.ca

CONTACT

Catherine Coolens, Ph. D

416-946-5011

catherine.coolens@rmp.uhn.ca

CONTACT