Development of Urologic Registry for Personalized Medicine in Patients With Urological Malignancy by Analyzing Circulating Tumor DNA
Recruiting
Observational Study
Prostate CancerRenal Cell CancerBladder CancerUreter Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
20 and older
Sex
Any
Study type
Observational
Participants needed
3,000 (estimated)
Sponsor
Yonsei University · Other
Who this trial is looking for
This trial is looking for patients with bladder, prostate, renal, or ureter cancer who have had surgery in the past few years. Participants will help researchers understand how circulating tumor DNA can be used for diagnosis and monitoring their condition.
Are You a Good Fit for This Trial?
You may be able to join if
I have been diagnosed with bladder cancer
I have been diagnosed with prostate cancer
I have been diagnosed with renal cell cancer
I have been diagnosed with ureter cancer
I have had surgery for my urological cancer since December 2019
I agree to allow my medical information to be used for this study
I agree to participate in this study
You may not be able to join if
I do not agree to participate in this study
I am in a situation where I might feel pressured to join or can't make my own decisions
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
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Urological malignancies such as prostate cancer and renal cell cancer in Korean population have been increased due to the aged population and the westernized lifestyles. With the advancement of sequencing technologies, use of genetic mutation profiles in cancer detection and progression has been increased. However, use of circulating tumor DNA in urological malignances have been limited and few st…
Urological malignancies such as prostate cancer and renal cell cancer in Korean population have been increased due to the aged population and the westernized lifestyles. With the advancement of sequencing technologies, use of genetic mutation profiles in cancer detection and progression has been increased. However, use of circulating tumor DNA in urological malignances have been limited and few studies have been reported. Therefore, we tried to evaluate the usefulness of circulating tumor DNA in detection and monitoring of urological malignancies in Korean population. This study aims to use circulating tumor DNA in plasma and urine for the diagnosis, disease progression monitoring and therapeutic response evaluation. This study plan includes building big databases for circulating tumor DNA of urological malignancies in Korean population and to develop optimized circulating tumor DNA platform.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 1\. Patients diagnosed as urological malignances (prostate cancer, renal cell cancer, bladder cancer, and ureter cancer)
* 2\. Patients who have undergone surgeries due to urological malignancies in Severance Hospital, Sinchon from 2019.12 and 2029.11
* 3\. Those who agree to …
Inclusion Criteria:
* 1\. Patients diagnosed as urological malignances (prostate cancer, renal cell cancer, bladder cancer, and ureter cancer)
* 2\. Patients who have undergone surgeries due to urological malignancies in Severance Hospital, Sinchon from 2019.12 and 2029.11
* 3\. Those who agree to give permission to use their human source information - 4. Those who agree with this study
Exclusion Criteria:
* 1\. Those who do not agree with this study
* 2\. Vulnerable participants who are likely to be vulnerable to coercion or undue influence or lack decision-making
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