Opioid-Sparing and Pain-Reducing Properties of Syntocinon: A Dose-Effect Determination
Recruiting
Early Phase 1
Interventional Study
Pain
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 21 – 45
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 45 (estimated)
- Sponsor
- University of Florida · Other
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About This Trial
Some research suggests that administration of oxytocin with oxycodone may reduce its abuse liability and improve its ability to reduce pain. In a 6-session laboratory study, the investigators will be evaluating the effects of oxycodone and oxytocin (combined and separately, across sessions) on experimentally-induced pain, subjective effects, decision-making, and activation of different neural subs…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Individuals fluent in English will participate.
* Must report recreational use of opioids.
* Be within 20% of their ideal body weight.
* Are not currently experiencing chronic pain (pain on most days during the past 3 months)
* Have a systolic blood pressure of \<=140 and dias…
Contacts