Early Use of Airway Pressure Release Ventilation (APRV) in ARDS
Recruiting
N/A
Interventional Study
Acute Respiratory Distress Syndrome
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 80
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 150 (estimated)
- Sponsor
- Hospital Civil de Guadalajara · Other
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About This Trial
Airway pressure release ventilation (APRV) is a time-cycled, pressure controlled, intermittent mandatory ventilation mode with extreme inverse I:E ratios. Currently it is considered as a non-conventional ventilatory mode. The investigators aim to compare APRV with conventional mechanical ventilation (MV) in patients with acute respiratory distress syndrome (ARDS).
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Acute respiratory distress syndrome, according to the Berlin definition of ARDS, with adjusted pO2/FiO2 for altitude \<300, and less than 48 h of endotracheal mechanical ventilation
Exclusion Criteria:
* Pregnancy
* Less than 18 years-old
* Expected duration of mechanical ve…
Contacts