Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity
Recruiting
Observational Study
Obesity, Morbid
NASH - Nonalcoholic Steatohepatitis
Chronic Inflammation
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 30 – 70
- Sex
- Any
- Study type
- Observational
- Participants needed
- 60 (estimated)
- Sponsor
- Mayo Clinic · Other
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Answer a few quick questions to see if you may meet the eligibility requirements.
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About This Trial
This study is being done to better understand the relationship between inflammation in adipose tissue (AT), abnormal deposition of fat around the liver and how this affects its appearance and function and ultimately insulin resistance.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Undergoing gastric bypass surgery
* Confirmed AUROC F=0 or F\>2 liver fibrosis
* Age 30-70 years
* BMI greater than 40 kg/m2
* Negative pregnancy test (female only)
* Lab Values: Normal TSH
Exclusion Criteria:
* Autoimmune diseases
* Hepatitis B or C positive
* Heavy alcohol…
Contacts