[18F]F-DOPA Imaging for Autonomic Failure
[18F]F-DOPA Imaging in Patients With Autonomic Failure
Recruiting
Phase 1
Interventional Study
Autonomic Failure
Pure Autonomic Failure
Parkinson Disease
Multiple System Atrophy
Dementia With Lewy Bodies
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 1
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 40 (estimated)
- Sponsor
- Daniel Claassen · Other
Who this trial is looking for
This trial is looking for adults with autonomic failure or related conditions. Participants will help researchers understand changes in brain function using a special imaging technique.
Are You a Good Fit for This Trial?
You may be able to join if
- I have been diagnosed with pure autonomic failure.
- I have autonomic failure and possible Parkinson's disease, MSA, or DLB.
- I am a healthy adult aged 18 or older.
- I have had a clinical exam confirming my condition.
You may not be able to join if
- I have any type of bioimplant that is mechanical or electronic.
- I have a ferromagnetic bioimplant that could be displaced.
- I have cerebral aneurysm clips.
- I may have shrapnel embedded in my body.
- I am pregnant.
- I am under 18 years old.
- I cannot give informed written consent.
- I have a mental ability that limits my ability to communicate.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
Alpha-synucleinopathies refer to age-related neurodegenerative and dementing disorders, characterized by the accumulation of alpha-synuclein in neurons and/or glia. The anatomical location of alpha-synuclein inclusions (Lewy Bodies) and the pattern of progressive neuronal death (e.g. caudal to rostral brainstem) give rise to distinct neurological phenotypes, including Parkinson's disease (PD), Mul…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Patients with a diagnosis if pure autonomic failure
2. Patients with autonomic failure and possible PD, MSA, or DLB
3. Healthy adults aged 18 and above
4. Clinical exam confirming clinical designation
Exclusion Criteria:
* Subjects who have any type of bioimplant activated …
Contacts