Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in Normal Tissue of Patients With Oral Cavity or Skull Base Tumors
Recruiting
Phase 4
Interventional Study
Malignant Oral Cavity Neoplasm
Malignant Skull Base Neoplasm
Osteoradionecrosis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 425 (estimated)
- Sponsor
- M.D. Anderson Cancer Center · Other
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
This phase IV trial studies how well serial magnetic resonance imaging (MRI) after radiation therapy works in predicting radiation-induced changes in the normal tissue of patients with oral cavity or skull base tumors. Performing MRIs after radiation therapy for patients with oral cavity or skull base tumors may help to predict osteoradionecrosis (a change in non-cancerous tissue).
Trial Locations
Loading…
Loading trial locations…
Eligibility Criteria
Inclusion Criteria:
All Cohorts:
* Patients older than 18 years of age
* Patients with good performance status (ECOG score 0-2)
* Patients willing to give written informed consent.
Cohort 1 (Individuals without ORN or MRONJ):
* Patients with histologically proven malignant neoplasms of the oral …
Contacts