Identification of Critical Thermal Environments for Aged Adults
Recruiting
Early Phase 1Interventional Study
Aging
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Trial phase
Early Phase 1
Study type
Interventional
Purpose
Basic Science
Participants needed
190 (estimated)
Sponsor
Penn State University · Other
Who this trial is looking for
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This study evaluates critical environmental limits (temperature and humidity) above which older adults are unable to effectively thermoregulate. Participants will exercise in a series of different environmental conditions to identify combinations of temperature and humidity above which age-related physiological changes cause uncompensable heat stress, resulting in increased risk of heat illness.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adults aged 18 and older (those 40+ years of age must be cleared by collaborating physician)
* All premenopausal women will be eumenorrheic (by survey)
* Asymptomatic and no signs/symptoms of disease according to the American College of Sports Medicine 10th edition Guidelines …
Inclusion Criteria:
* Adults aged 18 and older (those 40+ years of age must be cleared by collaborating physician)
* All premenopausal women will be eumenorrheic (by survey)
* Asymptomatic and no signs/symptoms of disease according to the American College of Sports Medicine 10th edition Guidelines for Exercise Testing and Prescription
Exclusion Criteria:
* Medications that affect thermoregulatory or cardiovascular responses to exercise
* Any contraindications to low intensity physical activity on the Physical Activity Readiness Questionnaire
* Any mobility restrictions that interfere with low intensity physical activity
* Pregnant or planning to become pregnant in the next 12 months
* Prior diagnosis of cancer, cardiovascular disease, diabetes, or metabolic syndrome
* Illegal/recreational drug use
* History of Chron's disease, diverticulitis, or similar gastrointestinal disease
* Abnormal resting or exercise electrocardiogram (ECG)
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