The DBCG Proton Trial: Photon Versus Proton Radiation Therapy for Early Breast Cancer
Recruiting
N/A
Interventional Study
Early Breast Cancer
Radiation Associated Cardiac Failure
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 1,502 (estimated)
- Sponsor
- Danish Breast Cancer Cooperative Group · Other
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About This Trial
The majority of early breast cancer patients are treated with adjuvant radiation therapy (RT) as part of their multimodal therapy. The aim of the RT is to lower the risk of local, regional and distant failure and improve survival. Modern RT is been provided with photon therapy. Now, more proton therapy facilities are opened, including in Denmark. Proton RT may have the potential to cause lower dos…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patient operated for early breast cancer with indication for radiation therapy, where standard planning shows a mean heart dose 4 Gy or more and/or a V20 lung of 37% or more.
* Boost (breast, chest wall and nodal), breast reconstruction (any type, except implants with metal), …
Contacts