Refusal of Breast Surgery in Patients With Breast Cancer With a Clinical Complete Response (cCR) After Neoadjuvant Systemic Therapy and a Confirmed Pathological Complete Response (pCR) Using Vacuum-assisted Biopsy (VAB) and Sentinel Lymph Node Biopsy (SLNB)

Recruiting N/A Interventional Study
Refusal of Breast Surgery in Patients With Breast Cancer With a cCR After NST and a Confirmed Pathological Complete Response (pCR) Using VAB and SLNB
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 70
Sex
Female
Study type
Interventional
Purpose
Treatment
Participants needed
60 (estimated)
Sponsor
N.N. Petrov National Medical Research Center of Oncology · Other
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About This Trial
The main goal of the study is to abandon breast surgery in patients with breast cancer with a clinical complete response (cCR) after neoadjuvant systemic therapy and confirmed pCR using Vacuum-assisted biopsy (VAB) and sentinel lymph node biopsy (SLNB). Evidence of the high diagnostic accuracy (sensitivity and specificity) of vacuum aspiration biopsy in determining pCR in patients with clinical c…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: Triple negative breast cancer / HER2-positive breast cancer (ER / PR +/-) * age\> 18 years. * morphologically confirmed diagnosis of breast cancer, IIA-IIIA stage * ECOG score 0-1. * life expectancy of more than 3 months. * the consent of patients to use reliable methods of con…
Contacts

Petr Krivorotko, MD,PhD

+79219597722

dr.krivorotko@mail.ru

CONTACT