Delayed Oophorectomy for Women at High Risk of Ovarian Cancer
TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention
- Age
- 25 – 50
- Sex
- Female
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 3,000 (estimated)
- Sponsor
- University Medical Center Nijmegen · Other
This trial is looking for women who have a specific gene mutation that increases their risk of ovarian cancer. Participants will undergo a procedure to remove their fallopian tubes and will have scheduled surgery to remove ovaries later.
You may be able to join if
- I have a class 5 BRCA1, BRCA2, RAD51C, RAD51D, or BRIP1 gene mutation.
- I am between 25 and 40 years old if I have the BRCA1 mutation.
- I am between 25 and 45 years old if I have the BRCA2 mutation.
- I am between 25 and 50 years old if I have the RAD51C, RAD51D, or BRIP1 mutation.
- I have completed my childbearing.
- I still have at least one fallopian tube.
- I can give informed consent for the study.
You may not be able to join if
- I am postmenopausal.
- I want a second surgery within two years after the first.
- I am legally incapable of giving consent.
- I have had a bilateral salpingectomy.
- I have a history of ovarian, fallopian tube, or peritoneal cancer.
- I currently have cancer or am undergoing treatment for cancer.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your EligibilityThe aim of the project is to evaluate the risk-reducing salpingectomy with delayed oophorectomy as an alternative for risk-reducing salpingo-oophorectomy in high risk women with respect to ovarian cancer incidence.
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