Delayed Oophorectomy for Women at High Risk of Ovarian Cancer
TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention
- Age
- 25 – 50
- Sex
- Female
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 3,000 (estimated)
- Sponsor
- University Medical Center Nijmegen · Other
This trial is looking for women who have a specific gene mutation that increases their risk of ovarian cancer. Participants will undergo a procedure to remove their fallopian tubes and will have scheduled surgery to remove ovaries later.
You may be able to join if
- I have a class 5 BRCA1, BRCA2, RAD51C, RAD51D, or BRIP1 gene mutation.
- I am between 25 and 40 years old if I have the BRCA1 mutation.
- I am between 25 and 45 years old if I have the BRCA2 mutation.
- I am between 25 and 50 years old if I have the RAD51C, RAD51D, or BRIP1 mutation.
- I have completed my childbearing.
- I still have at least one fallopian tube.
- I can give informed consent for the study.
You may not be able to join if
- I am postmenopausal.
- I want a second surgery within two years after the first.
- I am legally incapable of giving consent.
- I have had a bilateral salpingectomy.
- I have a history of ovarian, fallopian tube, or peritoneal cancer.
- I currently have cancer or am undergoing treatment for cancer.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your EligibilityThe aim of the project is to evaluate the risk-reducing salpingectomy with delayed oophorectomy as an alternative for risk-reducing salpingo-oophorectomy in high risk women with respect to ovarian cancer incidence.
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