Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB)

Recruiting Observational Study
Lung Injury Cardiopulmonary Bypass
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
Up to 12 Months
Sex
Any
Study type
Observational
Participants needed
56 (estimated)
Sponsor
Sophia Koutsogiannaki · Other
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About This Trial

Acute lung injury (ALI) following cardiopulmonary bypass (CPB) is a serious complication, often prolonging the length of stay in ICU and potentially dealing to mortality. The objective of this study is to assess the mechanism of CPB-mediated acute lung injury in pediatric patients.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Are \< 12months of age * Scheduled for cardiac surgical needing CPB * Preoperative SpO2 \> 90% Exclusion Criteria: * Lack of parental (or legal guardian's) consent * Preoperative SpO2 \< 90% * Preoperative oxygen therapy
Contacts

Sophia Koutsogiannaki, PhD

617-919-4725

sophia.koutsogiannaki@childrens.harvard.edu

CONTACT

Koichi Yuki, MD

617-355-6225

koichi.yuki@childrens.harvard.edu

CONTACT