Brain Health in Breast Cancer Survivors

Recruiting Observational Study
Cognitive Impairment Cognitive Function
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
35 – 65
Sex
Female
Study type
Observational
Participants needed
120 (estimated)
Sponsor
Jonsson Comprehensive Cancer Center · Other
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About This Trial
Endocrine therapy (ET) is widely used to treat hormone receptor positive breast cancer and prevent recurrence by downregulating estrogen function. However, ETs readily cross the blood brain barrier and interfere with the action of estrogen in the brain. Estrogen supports cognition and menopausal status is closely linked to cognitive health in women. This has raised concern that anti-estrogen ETs m…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age 35-65 * Fluent in English * Adequate vision/hearing to complete testing Exclusion Criteria: * History of major or mild neurocognitive disorder or dementia * Diagnosis of major neurological condition (e.g., epilepsy, Parkinson's Disease, stroke) * Diagnosis of a major psy…
Contacts

Kathleen Van Dyk, PhD

310 825-2719

KVanDyk@mednet.ucla.edu

CONTACT