Hormone Replacement Trial Against ALzheimers' Disease
Recruiting
N/A
Interventional Study
Postmenopausal Symptoms
Alzheimer Disease
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 40 – 65
- Sex
- Female
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 600 (estimated)
- Sponsor
- University Hospital, Ghent · Other
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About This Trial
The influence of postmenopausal hormone treatment on dementia is not clear. Dysfunctions in the metabolism of amyloid in the disease of Alzheimer result in an elevated presence of degradation products in cerebrospinal fluid.
The degradation products in blood will be analysed during the trial, to get better insight in menopause and the start of hormonal therapy.
Postmenopausal women with and with…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* postmenopausal women
* 40 - 65 years
Exclusion Criteria:
* Longer than 10 years in menopause
* thyroid dysfunction
* hypertension
* medical history of psychiatric comorbidity
* Alcohol and/or drug abuse
* medical history of neurologic symptoms with cognitive symptoms
Contacts