Metabolic Inflexibility is Related to Elevated Muscle Anaerobic Glycolysis
Recruiting
Observational Study
Metabolic Inflexibility
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 50
- Sex
- Any
- Study type
- Observational
- Participants needed
- 100 (estimated)
- Sponsor
- East Carolina University · Other
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About This Trial
The focus of this proposal is on overweight (25\>BMI\<30 kg/m2) subjects, as these individuals exhibit a high risk of becoming obese and/or developing metabolic diseases. We hypothesize that in some overweight individuals there is a "metabolic program" in skeletal muscle which predisposes them to the development of obesity. Findings may lead to clinical screening tools for determining risk for obe…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 18-50 years old
* BMI of 25 - 30 kg/m2
* BMI \> 40kg/m2
* Lactate levels in top and lower 25%
Exclusion Criteria:
* Pregnant women
* Mentally disabled
* Prisoners
* Smokers
* Subjects with heart disease
* Type 1 and 2 diabetes
* Endocrine disease
* Hypertension
* Musculoskel…
Contacts