No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
0 Months – 6 Months
Sex
Any
Study type
Observational
Participants needed
1,700 (estimated)
Sponsor
University of Pennsylvania · Other
Who this trial is looking for
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Early childhood detection of motor delays or impairments provides the opportunity for early treatment which improves health outcomes. This study will use state of the art sensors combined with machine learning algorithms to develop objective, accurate, easy-to-use tools for the early scoring of deficits and lays the foundation for the early prediction of physical disability.
Trial Locations
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Status
Eligibility Criteria
Infants, male and female, between 0-6 months (Infants older than 6 months before initial enrollment will be excluded).
* Infants with early brain injury (EBI):
* Hydrocephalus
* Hypoxic-ischemic encephalopathy (HIE)
* Periventricular leukomalacia (PVL)
* Intraventricular hemorrhage (IVH)
…
Infants, male and female, between 0-6 months (Infants older than 6 months before initial enrollment will be excluded).
* Infants with early brain injury (EBI):
* Hydrocephalus
* Hypoxic-ischemic encephalopathy (HIE)
* Periventricular leukomalacia (PVL)
* Intraventricular hemorrhage (IVH)
* Stroke
* Healthy infants (controls):
o No history of early brain injury (EBI)
* Infants without EBI/risk for future disability:
* Infants without known brain injuries, but with a history of preterm birth less than 32-week gestation with significant medical problems, difficulty eating, or who lack head control at 4 months of age or later will be classified as moderate risk.
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