Toward a Computationally-Informed, Personalized Treatment for Hallucinations

Inclusion Criteria: * Age 18-65 * English speaking * Right handedness * Diagnosed with schizophrenia schizoaffective, schizophreniform, schizotypal, or brief psychotic disorder * History of auditory verbal hallucinations occurring at least weekly Exclusion Criteria: * Current substance dependence or active use as determined by drug test. * Any neurological, medical or developmental problem that is known to impair cognition significantly * Contraindications for MR scanning including metallic implants of any kind, pacemakers and history of accidents with metal, claustrophobia * History of seizures * History of violence * History of suicide * Pregnancy (determined by urine pregnancy test) * Concurrent participation in any other intervention study * History of urinary retention * History of delirium * Current use of any cholinergic or anticholinergic medication * History of asthma, diabetes, and cardiovascular disease * Evidence of cardiovascular disease on EKG * Individuals who have been on dopamine-2 antagonists for less than 6 months (to limit risk of EPS)