Breast Conservation Treatment for Breast Cancer Recurrence
Personalized Second Chance Breast Conservation (PSCBC): A Prospective Phase II Clinical Study
Recruiting
N/A
Interventional Study
Breast Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 19 – 90
- Sex
- Female
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 120 (estimated)
- Sponsor
- Weill Medical College of Cornell University · Other
Who this trial is looking for
This trial is looking for women who have experienced a return of breast cancer after previous treatment. Participants will receive a type of radiation therapy to help preserve their breast tissue.
Are You a Good Fit for This Trial?
You may be able to join if
- I have an isolated breast cancer lesion that is unifocal
- My breast cancer lesion is smaller than 2-3 cm
- I have a confirmed diagnosis of invasive breast cancer or carcinoma in situ
- I have negative margins from my previous surgery
- I have 0 to 3 positive lymph nodes without extension outside the capsule
- I do not have any distant cancer spread
- I am at least 18 years old
- It has been at least 12 months since my initial breast cancer treatment
You may not be able to join if
- I have regional cancer recurrences in my axilla or supraclavicular area
- I have positive margins from my past surgery
- I have metastatic disease
- I have poor cosmetic results from previous surgery or treatment
- I have extensive intraductal component
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
The goal of the study is to investigate the feasibility of enabling a second chance for breast conservation in patients with in-breast recurrences after a previous lumpectomy and RT, investigators propose to test partial breast irradiation with the target volume encompassing the entire surgical bed with 1.0-1.5 cm margins.
An additional goal of the study is to investigate the feasibility of enabl…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Isolated ipsilateral unifocal breast lesions
* Limited size (\< 2-3 cm) without evidence of skin involvement
* Histologically proven invasive breast carcinoma or carcinoma in situ
* Negative histologic margins of resection
* Patients with 0 to 3 positive axillary lymph nodes w…
Contacts