No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
25 – 85
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
50 (estimated)
Sponsor
University of New Mexico · Other
Who this trial is looking for
This trial is looking for people who have had a stroke and now have difficulty speaking due to aphasia. Participants will undergo assessments and receive a treatment that combines speech therapy with a stimulation technique over 15 sessions.
Are You a Good Fit for This Trial?
You may be able to join if
I am aged between 25 and 85.
I am more than 6 months post-stroke.
I have been diagnosed with aphasia.
I had a stroke that affected the left side of my brain.
I can still learn to name objects.
You may not be able to join if
I have another neurological disease.
I have damage to the right side of my brain.
I have a significant mood disorder.
I have had a substance or alcohol abuse problem in the last year.
I have an implanted electrical device.
I have had medical instability in the last 4 weeks.
I am pregnant.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
62 patients who are one year post stroke and have Aphasia as a result of that stroke will be recruited. Participants will have 4 assessment sessions and 15 treatment sessions. The TDCS will be to right Inferior Frontal Gyrus (IFG) (25 active, 25 sham) for 15 days. A combined semantic feature analysis/phonological components analysis treatment will be paired with the stimulation. Two assessment ses…
62 patients who are one year post stroke and have Aphasia as a result of that stroke will be recruited. Participants will have 4 assessment sessions and 15 treatment sessions. The TDCS will be to right Inferior Frontal Gyrus (IFG) (25 active, 25 sham) for 15 days. A combined semantic feature analysis/phonological components analysis treatment will be paired with the stimulation. Two assessment sessions will be pretreatment, 1 session immediately post-treatment, and 1 session at 3 months follow-up.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. aged 25-85
2. must be greater than 6 months post-stroke
3. must have a diagnosis of aphasia based on impaired performance on the Western Aphasia Battery-Revised, Boston Naming Test, or during discourse production
4. must be left-hemisphere dominant as demonstrated by aphasia …
Inclusion Criteria:
1. aged 25-85
2. must be greater than 6 months post-stroke
3. must have a diagnosis of aphasia based on impaired performance on the Western Aphasia Battery-Revised, Boston Naming Test, or during discourse production
4. must be left-hemisphere dominant as demonstrated by aphasia onset subsequent to left hemisphere damage
5. must be stimulable for naming
Exclusion Criteria:
1. comorbid neurological disease.
2. damage to the anterior right hemisphere.
3. significant mood disorder.
4. substance/alcohol dependence or abuse within the past year
5. presence of any implanted electrical device or contraindications to tDCS or MRI
6. recent medical instability (within 4 weeks)
7. pregnancy
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