fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
Recruiting
Observational Study
Pain, Postoperative
Pain, Chronic
Pain, Acute
Surgical Injury
Surgical Wound
Cornea Injury
Cornea
Keratoconus
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 8 – 35
- Sex
- Any
- Study type
- Observational
- Participants needed
- 60 (estimated)
- Sponsor
- Boston Children's Hospital · Other
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About This Trial
Evaluation of neuroplasticity of pain pathways and corneal afferent nerve regeneration following corneal crosslinking (CXL) in keratoconus patients using fMRI and corneal In Vivo Confocal Microscopy (IVCM).
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
CXL Group
* Age 8-35 years
* Clinical diagnosis of keratoconus and seeking CXL treatment
* English speaking ability sufficient to comprehend consent with parental assistance
* MRI compatible
* Ability to lie still for an MRI session (60 minutes)
Control Group
* Age 8-35 years…
Contacts