Exercise Study for Pre-diabetes and Type 2 Diabetes
Mechanisms of Fatigability With Diabetes
Recruiting
N/A
Interventional Study
Pre-diabetes
Type 2 Diabetes
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 30 – 85
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 80 (estimated)
- Sponsor
- University of Michigan · Other
Who this trial is looking for
This trial is looking for adults with pre-diabetes or type 2 diabetes to participate in an exercise program. Participants will help researchers understand how blood flow affects exercise performance.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 30 and 85 years old.
- I have pre-diabetes.
- I have type 2 diabetes.
- I have normal blood sugar levels.
You may not be able to join if
- I have signs of nerve damage.
- I take insulin for diabetes.
- My blood sugar control is poor.
- I have swelling in my legs.
- I am severely overweight.
- I have untreated thyroid problems.
- I smoke.
- I have heart or muscle diseases that prevent exercise.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
Pre-diabetes (Pre-D) is a precursor to type 2 diabetes (T2D) and characterized by increased exercise fatigability of lower limb muscles, that can impede exercise performance. The cause for the increased fatigability in people with Pre-D is not known. Given the profound vascular disease present in people who have had uncontrolled diabetes for several years, we will determine whether dynamic, fatigu…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Men and women adults 30 years to 85 years or less
* Pre-diabetes \[glycosylated hemoglobin (HbA1c) of 5.7-6.4% and fasting plasma glucose 100-125 mg/dL at the time of initial screening\]
* Controls \[normoglycemic with a HbA1c level ≤5.6% and fasting blood glucose ≤ 99 mg/dL (…
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