Immune Homeostasis in Sepsis and Septic Shock

Recruiting Observational Study
Sepsis Immunologic Paralysis Immunologic Suppression Immune Deficiency
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
200 (estimated)
Sponsor
Charles University, Czech Republic · Other
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About This Trial

Detailed description of immune response and its dynamics in sepsis and septic shock patiens by means of transcriptomics, flow-cytometry and cytokine analysis.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * sepsis/septic shock (SEPSIS-3) * age ≥18 * informed consent * inclusion within first 24hrs after development/diagnosis of septic shock Exclusion Criteria: * disagreement of the patient or legal representative with the entry into the study * patients with primary or secondary…
Contacts

Thomas Karvunidis, MD, Ph.D.

+420 377 103 173

karvunidist@fnplzen.cz

CONTACT

Marcela Královcová, MD

+420 377 103 173

kralovcovam@fnplzen.cz

CONTACT