Spermatogonial Stem Cell (SSC) Transplant and Testicular Tissue Grafting
Recruiting
N/A
Interventional Study
Infertility, Male
Cancer
Autoimmune Disorder
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Sex
- Male
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 10 (estimated)
- Sponsor
- University of Pittsburgh · Other
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About This Trial
Spermatogonial stem cell transplantation through ultrasound guided rete testis injection and testicular tissue grafting will be performed for participants who have frozen testicular tissue prior to gonadotoxic therapy. The purpose of this study is to test the safety and feasibility of these transplant technologies and restore fertility for these participants.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Male participant at least in Tanner stage 3
* Previously cryopreserved and stored testicular tissue/cells (frozen due to an infertility-risking diagnosis or treatment such as chemotherapy or radiation) available for autologous transplantation and grafting
* Healthy enough to u…
Contacts