Focal Radiotherapy Plus Low Dose Craniospinal Irradiation Followed by Adjuvant Chemotherapy in WNT Medulloblastoma.
Recruiting
N/A
Interventional Study
Medulloblastoma, WNT-activated
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 3 – 16
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 30 (estimated)
- Sponsor
- Tata Memorial Centre · Other
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About This Trial
This clinical study is going to be done on a type of brain tumor in children called Medulloblastoma. The WNT pathway type of medulloblastoma is considered to be low risk and have the best outcomes in terms of survival. With the current standard of care for this type of medulloblastoma it is believed by the investigators that we are over treating the disease and increasing the long term side effect…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age more than 3 years and less than 16 years.
* Newly diagnosed WNT pathway medulloblastoma.
* Post-surgery residual disease less than 1.5 cm2 on post-operative MRI brain.
* No evidence of metastatic disease in the brain, spine or cerebral spinal fluid (CSF) assessed by MRI of…
Contacts