Low Dose Rosuvastatin Plus Ezetimibe Versus High-dose Rosuvastatin in AMI

Recruiting Phase 4 Interventional Study
Myocardial Infarction Statin Adverse Reaction HMG-CoA Reductase Inhibitor Toxicity
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
19 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
3,548 (estimated)
Sponsor
Kiyuk Chang, MD,PhD · Other
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About This Trial
Combination therapy of rosuvastatin 5mg and ezetimibe 10 mg showed similar achievement rate in decreasing LDL cholesterol level by 50% as single use of rosuvastatin 20 mg. This trial aims to prove non-inferiority of concomitant usage of low dose rosuvastatin and ezetimibe among patients with acute myocardial infarction who went through percutaneous coronary intervention at decreasing major advers…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Adults Aged 19 and up 2. Patients diagnosed with myocardial infarction (both ST segment elevation and non-ST segment elevation) who were treated with percutaneous coronary intervention (Myocardial infarction defined as in the 4th Universal Definition of Myocardial Infarction)…
Contacts

Kiyuk Chang, MD,PhD

82-10-9175-2076

kiyuk@catholic.ac.kr

CONTACT

Eun Ho Choo, MD

82-10-8500-4569

cmcchu@catholic.ac.kr

CONTACT